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Integrin alpha 7 (cleaved Glu959) antibody

Anti-Integrin alpha 7 (cleaved Glu959) antibody used in Western Blot (WB). GTX86894

Cat. No. GTX86894

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Monkey
Package
100 μg ($409)
See all Integrin alpha 7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

129 kDa. ( Note )

Product Note

Integrin alpha 7 (cleaved Glu959) antibody detects endogenous levels of fragment of activated ITGA7 resulting from cleavage adjacent to Glu959.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin alpha 7 (940-989).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ITGA7 , integrin subunit alpha 7 , Integrin alpha 7

Cellular Localization

Membrane

Background

The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES

Anti-Integrin alpha 7 (cleaved Glu959) antibody used in Western Blot (WB). GTX86894

GTX86894 WB Image

WB analysis of COS7 cells treated with etoposide 25uM (1h) lysate using GTX86894 Integrin alpha 7 (cleaved Glu959) antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409