GeneTex

  • Country / Location Selection

United States (US)

KCNMB1 antibody [N1C3]

Anti-KCNMB1 antibody [N1C3] used in Western Blot (WB). GTX105666
Anti-KCNMB1 antibody [N1C3] used in Western Blot (WB). GTX105666

Cat. No. GTX105666

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all KCNMB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:10000
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Positive Control

A431 , H1299 , Mouse heart

Predict Reactivity

Rat, Rabbit, Bovine, Dog, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human KCNMB1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037734

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium calcium-activated channel subfamily M regulatory beta subunit 1 , BKbeta1 , K(VCA)beta , SLO-BETA , hbeta1 , hslo-beta , k(VCA)beta-1 , slo-beta-1

Cellular Localization

Membrane; Multi-pass membrane protein

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-KCNMB1 antibody [N1C3] used in Western Blot (WB). GTX105666

GTX105666 WB Image

Sample (50 ug of whole cell lysate)
A: mouse heart
12% SDS PAGE
GTX105666 diluted at 1:10000

Anti-KCNMB1 antibody [N1C3] used in Western Blot (WB). GTX105666

GTX105666 WB Image

Sample (30 ug of whole cell lysate)
A: A431 (GTX27909)
B: H1299
12% SDS PAGE
GTX105666 diluted at 1:1000

REFERENCE

Application Reference

Barnes EA et al. Am J Physiol Lung Cell Mol Physiol 2018; 315 (2) : L265-L275 β1-Subunit of the calcium-sensitive potassium channel modulates the pulmonary vascular smooth muscle cell response to hypoxia.
Nieves-Cintron M et al. Sci Rep 2017; 7 (1) : 14058 Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for KCNMB1 antibody [N1C3] (GTX105666). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169