APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human fetal brain , mouse , rat brain
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human KIF5C.
Purification
Affinity Purified
Conjugation
Unconjugated
RRID
AB_11166978
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
kinesin family member 5C , CDCBM2 , KINN , NKHC , NKHC-2 , NKHC2
Cellular Localization
Cytoplasm, cytoskeleton,Cell projection, dendrite
Background
The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015]
Database
Research Area
DATA IMAGES
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GTX45388 WB Image
WB analysis of human fetal brain tissue using GTX45388 KIF5C antibody at 0.2-1μg/ml.
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GTX45388 WB Image
WB analysis of mouse and rat brain tissue using GTX45388 KIF5C antibody at 2μg/ml.
Lane 1 : Mouse brain tissue extract (80μg)
Lane 2 : Rat brain tissue extract (80μg)
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REFERENCE
REVIEW
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