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KSHV LANA2 antibody [CM-A807]

Anti-KSHV LANA2 antibody [CM-A807] used in Western Blot (WB). GTX30624

Cat. No. GTX30624

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CM-A807

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA

Reactivity

 Kaposi's sarcoma-associated herpesvirus
Package
100 μl ($409)
See all KSHV LANA2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 - 4 μg/ml
ICC/IF 1:10 - 1:500
IHC-P 1:10 - 1:500
IHC-Fr 1:10 - 1:500
IP 1:10 - 1:500
ELISA 1:100 - 1:2000
Not tested in other applications.

Product Note

This is specific for KSHV LANA2 (residues 143-310 epitope recognition).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Kaposi's sarcoma-associated herpesvirus

Immunogen

Recombinant LANA2 fusion protein.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Kaposi's sarcoma-associated herpesvirus LANA2 , HHV-8 LANA2 , Human herpesvirus 8 LANA2

Background

LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist. It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes virus 8. It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castleman's disease). It does not appear to be expressed in KS (Kaposi's sarcoma) lesions.

Research Area

DATA IMAGES

Anti-KSHV LANA2 antibody [CM-A807] used in Western Blot (WB). GTX30624

GTX30624 WB Image

WB analysis of infected lysate using GTX30624 KSHV LANA2 antibody [CM-A807].
Lane 1: BCBL-1 cell(KSHV+)
Lane 2: BC-1 cell(KSHV+/EBV+)
Lane 3: BCP-1 cell(KSHV+)
Loading : 30μg
Dilution : 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409