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Ku80 antibody [MEM-54]

Anti-Ku80 antibody [MEM-54] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79937

Cat. No. GTX79937

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-54

Isotype

 IgG2a

Application

 ICC/IF, IP

Reactivity

 Human
Package
100 μg ($399)
See all Ku80 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

83 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

human whole T-lymphocytes

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11174341

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

KARP1 , KU80 , KUB2 , Ku86 , NFIV , XRCC5 , Xray repair cross complementing 5 , Ku80 , X-ray repair cross complementing 5

Cellular Localization

Nucleus,Nucleolus,Chromosome

Background

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ku80 antibody [MEM-54] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79937

GTX79937 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX79937 Ku80 antibody [MEM-54].
Green : Primary antibody
Red : Actin
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399