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Kv2.1 antibody

Anti-Kv2.1 antibody used in IHC (Paraffin sections) (IHC-P). GTX87498
Anti-Kv2.1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87498

Cat. No. GTX87498

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P

Reactivity

 Human, Monkey
Package
100 μg ($399)
See all Kv2.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100~1:500
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Kv2.1 (533-582).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

DRK1 , KCNB1 , Kv2.1 , potassium voltagegated channel subfamily B member 1 , potassium voltage-gated channel subfamily B member 1

Cellular Localization

Cell membrane,Perikaryon,Cell projection,Axon,Cell projection,Dendrite,Membrane,Cell junction,Synapse,Postsynaptic cell membrane,Cell junction,Synapse,Cell junction,Synapse,Synaptosome,Lateral cell membrane,Cell membrane,Sarcolemma

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Kv2.1 antibody used in IHC (Paraffin sections) (IHC-P). GTX87498

GTX87498 IHC-P Image

IHC-P analysis of human brain tissue using GTX87498 Kv2.1 antibody. The picture on the right is blocked with the synthesized peptide.

Anti-Kv2.1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87498

GTX87498 ICC/IF Image

ICC/IF analysis of COS7 cells using GTX87498 Kv2.1 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399