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LAMP1 antibody

Anti-LAMP1 antibody used in Western Blot (WB). GTX19294
Anti-LAMP1 antibody used in Western Blot (WB). GTX19294

Cat. No. GTX19294

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all LAMP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:250 - 1:1000
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

Product Note

In immunofluorescence procedures, this antibody stains Lamp1 in HeLa cells resulting in perinuclear staining.

PROPERTIES

Form

Liquid

Buffer

0.02M Tris pH7.4, 0.1M Glycine

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues C K(407) R S H A G Y Q T I(416) of human LAMP1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_423508

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lysosomal associated membrane protein 1 , CD107a , LAMPA , LGP120

Cellular Localization

Cell membrane,Lysosome membrane

Background

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-LAMP1 antibody used in Western Blot (WB). GTX19294

GTX19294 WB Image

WB analysis of 20 μg of HeLa cell lysate using GTX19294 LAMP1 antibody.
Dilution : 1:500

Anti-LAMP1 antibody used in Western Blot (WB). GTX19294

GTX19294 WB Image

The data was published in the journal Nat Commun in 2019. PMID: 30846695

REFERENCE

Application Reference

Carballo-Carbajal I et al. Nat Commun 2019; 10 (1) : 973 Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis.
Bove J et al. Autophagy 2014; 10 (5) : 889-900 BAX channel activity mediates lysosomal disruption linked to Parkinson disease.
Application : WB
Reactivity : Human
Dehay B et al. J Neurosci 2010; 30 (37) : 12535-44 Pathogenic lysosomal depletion in Parkinson's disease.
Reactivity : Mouse
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399