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LEMD3 antibody

Anti-LEMD3 antibody used in Western Blot (WB). GTX17158
Anti-LEMD3 antibody used in IHC (Paraffin sections) (IHC-P). GTX17158
Anti-LEMD3 antibody used in IHC (Paraffin sections) (IHC-P). GTX17158

Cat. No. GTX17158

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all LEMD3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

100 kDa. ( Note )

Positive Control

Human Colon Tissue Lysate(GTX27928)

Product Note

At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

LEMD3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3.The immunogen is located within the last 50 amino acids of LEMD3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LEM domain containing 3 , MAN1

Cellular Localization

Nucleus inner membrane

Background

This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-LEMD3 antibody used in Western Blot (WB). GTX17158

GTX17158 WB Image

WB analysis of human colon tissue lysate using GTX17158 LEMD3 antibody.
Working concentration : 1 μg/ml

Anti-LEMD3 antibody used in IHC (Paraffin sections) (IHC-P). GTX17158

GTX17158 IHC-P Image

IHC-P analysis of human colon tissue using GTX17158 LEMD3 antibody.
Working concentration : 2.5 μg/ml

Anti-LEMD3 antibody used in IHC (Paraffin sections) (IHC-P). GTX17158

GTX17158 IHC-P Image

IHC-P analysis of human colon tissue using GTX17158 LEMD3 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399