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LIGHT antibody [8C34]

Anti-LIGHT antibody [8C34] used in Western Blot (WB). GTX52911

Cat. No. GTX52911

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8C34

Isotype

 IgG1

Application

 WB, FACS

Reactivity

 Human
Package
100 μg ($399)
See all LIGHT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
FACS 1:50 - 1:200
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TNFSF14 EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD258 , HVEML , LIGHT , LTg , TNFSF14 , tumor necrosis factor superfamily member 14 , TNF superfamily member 14

Cellular Localization

Cell membrane,Secreted,Cytoplasm

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-LIGHT antibody [8C34] used in Western Blot (WB). GTX52911

GTX52911 WB Image

WB analysis of HEK293 expressing human TNFSF14 using GTX52911 LIGHT antibody [8C34].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399