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LONP1 antibody

Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596
Anti-LONP1 antibody used in Western Blot (WB). GTX51596
Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596
Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596

Cat. No. GTX51596

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all LONP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
IHC-P 1:50-400
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human LONP1(375-420).

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_2887782

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lon peptidase 1, mitochondrial , CODASS , LON , LONP , LonHS , PIM1 , PRSS15 , hLON

Cellular Localization

Mitochondrion matrix

Background

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]

Database

Research Area

DATA IMAGES

Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596

GTX51596 IHC-P Image

IHC-P analysis of human cervical carcinoma tissue using GTX51596 LONP1 antibody.
Dilution : 1:200

Anti-LONP1 antibody used in Western Blot (WB). GTX51596

GTX51596 WB Image

WB analysis of various samples using GTX51596 LONP1 antibody.
Dilution : 1:200
Lane 1 : mouse kidney lysates
Lane 2 : mouse intestine lysates

Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596

GTX51596 IHC-P Image

IHC-P analysis of rat colon tissue using GTX51596 LONP1 antibody.
Dilution : 1:200

Anti-LONP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX51596

GTX51596 IHC-P Image

IHC-P analysis of rat lung tissue using GTX51596 LONP1 antibody.
Dilution : 1:200

REFERENCE

Application Reference

Xu M et al. Cardiovasc Res 2018; (Epub) Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway.
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399