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LOX antibody [6B11]

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182
Anti-LOX antibody [6B11] used in Western Blot (WB). GTX84182

Cat. No. GTX84182

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6B11

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μl ($519)
See all LOX products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000
ICC/IF 1:100
IHC-P 1:50
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_10734013

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lysyl oxidase , AAT10

Cellular Localization

Secreted

Background

Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.

Database

Research Area

DATA IMAGES

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human colon tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human bladder carcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human prostate carcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human prostate tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84182

GTX84182 ICC/IF Image

ICC/IF analysis of COS7 cells transiently transfected with LOX plasmid using GTX84182 LOX antibody [6B11].

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human breast adenocarcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human liver tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human endometrium tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human thyroid tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human ovary adenocarcinoma tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in IHC (Paraffin sections) (IHC-P). GTX84182

GTX84182 IHC-P Image

IHC-P analysis of human kidney tissue using GTX84182 LOX antibody [6B11].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

Anti-LOX antibody [6B11] used in Western Blot (WB). GTX84182

GTX84182 WB Image

WB analysis of HEK293T cells transfected with LOX plasmid (Right) or empty vector (Left) for 48 hrs using GTX84182 LOX antibody [6B11].
Loading : 5 ug per lane

REFERENCE

Application Reference

Wang C et al. Biotechnol Lett 2020; 42 (8) : 1567-1579 Mechanical injury and IL-1β regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes.
Application : WB
Reactivity : Human
Goggins E et al. Neoplasia 2017; 30 (2) : 131-139 Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519