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M-Cadherin antibody

Anti-M-Cadherin antibody used in IHC (Paraffin sections) (IHC-P). GTX17434
Anti-M-Cadherin antibody used in Western Blot (WB). GTX17434

Cat. No. GTX17434

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all M-Cadherin products

APPLICATION

Application Note

WB: 1:500 - 1:1000, IHC: 1:50 - 1:200

Calculated MW

89 kDa. ( Note )

Product Note

M-cadherin (A108) pAb detects endogenous levels of M-cadherin protein.

PROPERTIES

Form

Liquid

Buffer

PBS pH7

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 80-130 of Human M-cadherin.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cadherin 15 , CDH14 , CDH3 , CDHM , MCAD , MRD3

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-M-Cadherin antibody used in IHC (Paraffin sections) (IHC-P). GTX17434

GTX17434 IHC-P Image

Immunohistochemistry (IHC) analyzes of M-cadherin (GTX17434) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Anti-M-Cadherin antibody used in Western Blot (WB). GTX17434

GTX17434 WB Image

Western blot (WB) analysis of M-cadherin (GTX17434)) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Mouse brain tissue lysate Lane3:Rat brain tissue lysate

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399