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MAPKBP1 antibody

Anti-MAPKBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65625
Anti-MAPKBP1 antibody used in Western Blot (WB). GTX65625
Anti-MAPKBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65625

Cat. No. GTX65625

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MAPKBP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

164 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mitogen-activated protein kinase binding protein 1 , JNKBP-1 , JNKBP1 , NPHP20

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]

Database

Research Area

DATA IMAGES

Anti-MAPKBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65625

GTX65625 IHC-P Image

IHC-P analysis of human stomach tissue using GTX65625 MAPKBP1 antibody.
Dilution : 1:100

Anti-MAPKBP1 antibody used in Western Blot (WB). GTX65625

GTX65625 WB Image

WB analysis of various sample lysates using GTX65625 MAPKBP1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-MAPKBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65625

GTX65625 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX65625 MAPKBP1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399