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MATN1 antibody

Anti-MATN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85289
Anti-MATN1 antibody used in Western Blot (WB). GTX85289
Anti-MATN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85289

Cat. No. GTX85289

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all MATN1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

Rat Liver Tissue Lysate(GTX27943) , Human Liver Tissue Slide

Product Note

This antibody is specific for MATN1 C-Terminus

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MATN1 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN1.The immunogen is located within amino acids 370 - 420 of MATN1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrilin 1 , CMP , CRTM

Background

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Database

Research Area

DATA IMAGES

Anti-MATN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85289

GTX85289 IHC-P Image

IHC-P analysis of human liver tissue using GTX85289 MATN1 antibody.
Working concentration : 20 μg/ml

Anti-MATN1 antibody used in Western Blot (WB). GTX85289

GTX85289 WB Image

WB analysis of rat liver tissue lysate using GTX85289 MATN1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-MATN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX85289

GTX85289 IHC-P Image

IHC-P analysis of human liver tissue using GTX85289 MATN1 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399