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MBL2 antibody [3E7]

Cat. No. GTX54434

Host

Mouse

Clonality

Monoclonal

Clone Name

3E7

Isotype

IgG1

Application

IHC-Fr, FACS, ELISA, Neutralizing/Inhibition

Reactivity

Human
Package
50 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
FACS 6.5 μg/ml
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

IHC-Fr
Tissue sections embedded in ornithine carbamoyltransferase compound were frozen in acetone dry ice and immersed in Tris-buffered saline (TBS) three times for 5 minutes. Treatment in 0.5% hydrogen peroxide in methanol solution has been done to quench endogenous peroxidase activity.

Neutralizing/Inhibition
Pretreatment of sheep erythrocytes with antibody 3E7 suppressed hemolysis in a dose dependent manner.

Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Serum isolated human RaRF

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

COLEC1,HSMBPC,MBL,MBL2,MBL2D,MBP,MBP1,MBPC,MBPD,mannose binding lectin 2,MBL-C,Mannan Binding Lectin,Mannose-binding protein C

Cellular Localization

Secreted

Background

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399