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MHC Class I H-2Kk + H-2Dk antibody [16-1-2N (HB14)]

Cat. No. GTX03744

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 16-1-2N (HB14)

Isotype

 IgG2a

Application

 FACS, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($399)
See all MHC Class I H-2Kk + H-2Dk products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
The neutralizing/inhibition assay of clone 16-1-2N (HB14) is based on PMID: 9539772, 3006052.
Not tested in other applications.

Product Note

The 16-1-2N monoclonal antibody is reported to react with the mouse H-2Kk and H-2Dk MHC class I alloantigens.

PROPERTIES

Form

Liquid

Buffer

0.2 μM filtered PBS pH 7.0

Preservative

No preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

C3H mouse spleen cells

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% by SDS-PAGE

Endotoxin

<2EU/mg (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Research Area

REFERENCE

Clone Reference

Y Kusunoki et al. Blood 1998; 91 (11):4038-44 Prevention of marrow graft rejection without induction of graft-versus-host disease by a cytotoxic T-cell clone that recognizes recipient alloantigens
Application : FACS
H Jiang et al. Proc Natl Acad Sci U S A 1998; 95 (8):4533-7 T cell vaccination induces T cell receptor Vbeta-specific Qa-1-restricted regulatory CD8(+) T cells
Application : Neutralizing/Inhibition
H C O'Neill et al. Proc Natl Acad Sci U S A 1986; 83 (5):1443-7 Monoclonal antibodies specific for H-2K and H-2D antigens on cytotoxic T cells can inhibit their function
Application : Neutralizing/Inhibition
Submit a Reference

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Package List Price ($)
$ 399