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MMP14 antibody [9E10]

Anti-MMP14 antibody [9E10] used in IHC (Paraffin sections) (IHC-P). GTX52480

Cat. No. GTX52480

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 9E10

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MMP14 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:400 - 1:800
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Product Note

This antibody recognizes human MMP-14 in western blot without cross reactivity with human MMP-1-13, and MMP14-15.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-14

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MMP14 , MMPX1 , MT1MMP , MTMMP , MTMMP 1 , MTMMP1 , WNCHRS , matrix metallopeptidase 14

Cellular Localization

Membrane,Melanosome,Cytoplasm

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP14 antibody [9E10] used in IHC (Paraffin sections) (IHC-P). GTX52480

GTX52480 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52480 MMP14 antibody [9E10].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399