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MMP15 antibody [5D11]

Anti-MMP15 antibody [5D11] used in Western Blot (WB). GTX52481
Anti-MMP15 antibody [5D11] used in IHC (Paraffin sections) (IHC-P). GTX52481

Cat. No. GTX52481

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5D11

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MMP15 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:400 - 1:1000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Product Note

This antibody recognizes human MMP-15 in western blot without cross reactivity with human MMP-14/16.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-15

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MMP15 , MT2MMP , MTMMP2 , SMCP2 , matrix metallopeptidase 15

Cellular Localization

Membrane

Background

This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-MMP15 antibody [5D11] used in Western Blot (WB). GTX52481

GTX52481 WB Image

WB analysis of human placenta tissue lysates using GTX52481 MMP15 antibody [5D11].

Anti-MMP15 antibody [5D11] used in IHC (Paraffin sections) (IHC-P). GTX52481

GTX52481 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52481 MMP15 antibody [5D11].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399