GeneTex

  • Country / Location Selection

United States (US)

MMP23 antibody

Cat. No. GTX11644

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr, IP, ELISA

Reactivity

 Human
Package
25 μg ($399)
See all MMP23 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1,000
IHC-Fr Assay dependent
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Product Note

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.4, 50% Glycerol

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

~1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 23B , MIFR , MIFR-1 , MMP22 , MMP23A

Cellular Localization

Endoplasmic reticulum membrane,Membrane

Background

Matrix Metalloproteinase 23 (MMP21, MMP22, MIFR2, CAMMP) was first described in tumor cells. MMP23 shares much of the same domain structure as the classical MMPs, but has a unique cysteine array. The cysteine switch that is found in the classical MMPs is lacking or has a different sequence in MMP23. MMP23 has a furin cleavage site and it is thought to be localized within the cell. MMP23 has been reported as splice variants with different truncations at its C-terminus. MMP23 is predominantly expressed in ovary, testis, and prostate indicating that it plays a specialized role in reproductive processes. The human MMP23 gene has the chromosomal location of 1p36.3. The chromosome 1 location is a unique position among all the MMP genes currently mapped.

Database

Research Area

REFERENCE

There are currently no references for MMP23 antibody (GTX11644). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MMP23 antibody (GTX11644). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399