GeneTex

  • Country / Location Selection

United States (US)

MMP3 antibody [3E44]

Anti-MMP3 antibody [3E44] used in IHC (Paraffin sections) (IHC-P). GTX52474
Anti-MMP3 antibody [3E44] used in Western Blot (WB). GTX52474

Cat. No. GTX52474

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3E44

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MMP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:200 - 1:400
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Product Note

This antibody recognizes human MMP-3 in western blot without cross reactivity with other human MMPs.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-3

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CHDS6 , MMP3 , SL1 , STMY , STMY1 , STR1 , matrix metallopeptidase 3

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP3 antibody [3E44] used in IHC (Paraffin sections) (IHC-P). GTX52474

GTX52474 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52474 MMP3 antibody [3E44].

Anti-MMP3 antibody [3E44] used in Western Blot (WB). GTX52474

GTX52474 WB Image

WB analysis of culture supernatant from human fibroblasts stimulated with or without 50ng/ml of IL-12 for 6 hours using GTX52474 MMP3 antibody [3E44].

REFERENCE

There are currently no references for MMP3 antibody [3E44] (GTX52474). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MMP3 antibody [3E44] (GTX52474). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Package List Price ($)
$ 399