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MT2 antibody

Anti-MT2 antibody used in Western Blot (WB). GTX129715
Anti-MT2 antibody used in Western Blot (WB). GTX129715

Cat. No. GTX129715

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all MT2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

K562 , THP-1 , U87-MG , SK-N-SH , IMR32 , SK-N-AS

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain of human Melatonin Receptor 1B. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2886078

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

melatonin receptor 1B , FGQTL2 , MEL-1B-R , MT2

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-MT2 antibody used in Western Blot (WB). GTX129715

GTX129715 WB Image

Melatonin Receptor 1B antibody detects Melatonin Receptor 1B protein by western blot analysis.
A. 30 μg K562 whole cell lysate/extract
B. 30 μg THP-1 whole cell lysate/extract
12 % SDS-PAGE
Melatonin Receptor 1B antibody (GTX129715) dilution: 1:1000

Anti-MT2 antibody used in Western Blot (WB). GTX129715

GTX129715 WB Image

Melatonin Receptor 1B antibody detects Melatonin Receptor 1B protein by western blot analysis.
A. 30 μg U87-MG whole cell lysate/extract
B. 30 μg SK-N-SH whole cell lysate/extract
C. 30 μg IMR32 whole cell lysate/extract
D. 30 μg SK-N-AS whole cell lysate/extract
12 % SDS-PAGE
Melatonin Receptor 1B antibody (GTX129715) dilution: 1:1000

REFERENCE

Application Reference

Sasaki H et al. Am J Physiol Lung Cell Mol Physiol 2021; 321 (6) : L991-L1005 Melatonin MT(2) receptor is expressed and potentiates contraction in human airway smooth muscle.
Application : WB
Reactivity : Human
Chen CC et al. Cancers (Basel) 2018; 10 (9) Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399
$ 169