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MUC5B antibody

Anti-MUC5B antibody used in Western Blot (WB). GTX17503

Cat. No. GTX17503

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($439)
See all MUC5B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-3000
Not tested in other applications.

Calculated MW

596 kDa. ( Note )

Product Note

MUC5B Antibody detects endogenous levels of total MUC5B

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Muc5B

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mucin 5B, oligomeric mucus/gel-forming , MG1 , MUC-5B , MUC5 , MUC9

Cellular Localization

Secreted

Background

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-MUC5B antibody used in Western Blot (WB). GTX17503

GTX17503 WB Image

WB analysis of COLO205 cell lysate using GTX17503 MUC5B antibody.

REFERENCE

Application Reference

Iwashita J et al. Front Pharmacol 2022; 13 : 851374 Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 439