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MVP/LRP antibody [LRP-56]

Cat. No. GTX23367

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 LRP-56

Isotype

 IgG2b

Application

 ICC/IF, IHC-P, IHC-Fr, FACS

Reactivity

 Human
Package
500 μl ($399)
See all MVP/LRP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 1:10 - 1:40
IHC-Fr 1:10 - 1:40
FACS Assay dependent

Note :

IHC-P
Pretreatment is not required. For optimal staining, the primary antibody should be incubated overnight at 4ºC.

IHC-Fr
Pretreatment is not required. For optimal staining, the primary antibody should be incubated overnight at 4ºC.
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

Lung, Colon, kidney, bronchus or adrenal cortex (human tissue). Also in MDR cell lines such as GLC4/ADR, HT1080/DR4 & 2R120.Negative control antibody: Normal mouse serum

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant, 1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

2R120 cell line derived by stepwise Doxorubicin exposure of the the SW-1573 non-small cell lung carcinoma cell line.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

major vault protein , LRP , VAULT1

Cellular Localization

Cytoplasm

Background

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399