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Melanoma antibody [HMB45+A103+T311]

Anti-Melanoma antibody [HMB45+A103+T311] used in IHC (Paraffin sections) (IHC-P). GTX14203

Cat. No. GTX14203

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HMB45+A103+T311

Isotype

 IgG1, IgG2a

Application

 IHC-P

Reactivity

 Human
Package
200 μl ($399)
See all Melanoma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25-1:50

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

Product Note

The HMB45 clone reacts with a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. Clone A103 recognizes a protein of 20 kDa, identified as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. Tyrosinase is a key enzyme involved in the initial stages of melanin biosynthesis. The combination of HMB45, MART-1 and tyrosinase make this triple antibody cocktail a first-order pan melanoma screener.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Pigmented melanoma metastases from lymph nodes (HMB45). Recombinant human MART-1 protein (A103). Recombinant tyrosinase protein T311.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Research Area

DATA IMAGES

Anti-Melanoma antibody [HMB45+A103+T311] used in IHC (Paraffin sections) (IHC-P). GTX14203

GTX14203 IHC-P Image

IHC-P analysis of human metastatic melanoma in lymph node tissue using GTX14203 Melanoma antibody [HMB45+A103+T311].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399