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Melanoma antibody [PNL2]

Anti-Melanoma antibody [PNL2] used in IHC (Paraffin sections) (IHC-P). GTX12502
Anti-Melanoma antibody [PNL2] used in IHC (Paraffin sections) (IHC-P). GTX12502

Cat. No. GTX12502

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PNL2

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
250 μl ($399)
See all Melanoma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
Not tested in other applications.

Product Note

This antibody may be most useful because of its high sensitivity for metastatic melanoma (87%), as opposed to 76% for anti-HMB45 and 82% for anti- MART-1. Anti-PNL2 labels intra-epidermal nevi while the dermal component of compound nevi are largely non-reactive with anti-PNL2. Antibodies against PNL2, MART-1 (Melan A) and HMB45 stain most clear cell sarcoma cells and a few cells in angio-myolipomas and lymphangioleiomyomatosis. Anti-PNL2 is a useful antibody for the identification of melanomas and clear cell sarcomas. Differential diagnosis is aided by the results from a panel of antibodies, including antibodies against HMB45, MART-1, tyrosinase, and MiTF.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Research Area

DATA IMAGES

Anti-Melanoma antibody [PNL2] used in IHC (Paraffin sections) (IHC-P). GTX12502

GTX12502 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX12502 Melanoma antibody [PNL2].

Anti-Melanoma antibody [PNL2] used in IHC (Paraffin sections) (IHC-P). GTX12502

GTX12502 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX12502 Melanoma antibody [PNL2] with GTX03614 10X Rapid Histo-Sealer.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399