GeneTex

  • Country / Location Selection

United States (US)

Melanophilin antibody

Anti-Melanophilin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33313
Anti-Melanophilin antibody used in Western Blot (WB). GTX33313
Anti-Melanophilin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33313

Cat. No. GTX33313

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Melanophilin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 301-600 of human MLPH (NP_077006.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

melanophilin , SLAC2-A

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-Melanophilin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33313

GTX33313 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX33313 Melanophilin antibody.
Blue : DAPI
Dilution : 1:100

Anti-Melanophilin antibody used in Western Blot (WB). GTX33313

GTX33313 WB Image

WB analysis of mouse stomach tissue lysate using GTX33313 Melanophilin antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Melanophilin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33313

GTX33313 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX33313 Melanophilin antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

There are currently no references for Melanophilin antibody (GTX33313). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Melanophilin antibody (GTX33313). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399