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Munc 13-4 antibody, C-term

Anti-Munc 13-4 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX15723

Cat. No. GTX15723

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all Munc 13-4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5μg/ml
Not tested in other applications.

Calculated MW

123 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX15723-PEP).

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KQASQHALRPAP, from the C Terminus of the protein sequence according to NP_954712.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

unc-13 homolog D , FHL3 , HLH3 , HPLH3 , Munc13-4

Cellular Localization

Cytoplasm , Lysosome

Background

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Munc 13-4 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX15723

GTX15723 IHC-P Image

IHC-P analysis of human spleen using GTX15723 Munc 13-4 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399