APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| WB: 0.2-2.5 μg/ml |
| IHC-P: 2-10 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Zebrafish, Yeast, Rabbit, Bovine, Dog, Guinea pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 - 1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MXI1
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
MAX interactor 1, dimerization protein , MAD2 , MXD2 , MXI , bHLHc11
Cellular Localization
Nucleus
Background
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX33961 IHC-P Image
IHC-P analysis of human lung tissue using GTX33961 Mxi1 antibody.
Concentration : 4.0-8.0μg/ml
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GTX33961 WB Image
WB analysis of human brain tissue lysate using GTX33961 Mxi1 antibody.
Concentration : 0.2-1μg/ml
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GTX33961 IHC-P Image
IHC-P analysis of human lung tissue using GTX33961 Mxi1 antibody.
Concentration : 5μg/ml
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REFERENCE
There are currently no references for Mxi1 antibody (GTX33961). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Mxi1 antibody (GTX33961). Be the first to share your experience with this product.
