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Myelin PLP antibody

Anti-Myelin PLP antibody used in Immunohistochemistry (IHC). GTX85465

Cat. No. GTX85465

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 ICC/IF, IHC

Reactivity

 Human, Mouse
Package
50 μg ($399)
See all Myelin PLP products

APPLICATION

Application Note

Recommended starting dilutions: For IHC/IF: Use at 1:1000 - 1:2000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

30 kDa. ( Note )

Product Note

proteolipid protein 1

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptides

Purification

Affinity purified antibody

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proteolipid protein 1 , GPM6C , HLD1 , MMPL , PLP , PLP/DM20 , PMD , SPG2

Cellular Localization

Cell membrane

Background

This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]

Database

Research Area

DATA IMAGES

Anti-Myelin PLP antibody used in Immunohistochemistry (IHC). GTX85465

GTX85465 IHC Image

In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399