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NCX1 antibody, Internal

Anti-NCX1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80928
Anti-NCX1 antibody, Internal used in Flow cytometry (FACS). GTX80928
Anti-NCX1 antibody, Internal used in Western Blot (WB). GTX80928

Cat. No. GTX80928

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all NCX1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

109 kDa. ( Note )

Predict Reactivity

Rat, Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human SLC8A1.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

RRID

AB_11172722

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 8 member A1 , NCX1

Cellular Localization

Cell membrane

Background

In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]

Database

Research Area

DATA IMAGES

Anti-NCX1 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80928

GTX80928 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX80928 NCX1 antibody, Internal.

Anti-NCX1 antibody, Internal used in Flow cytometry (FACS). GTX80928

GTX80928 FACS Image

FACS analysis of HL-60 cells using GTX80928 NCX1 antibody, Internal.
Green : primary antibody
Blue : negative control

Anti-NCX1 antibody, Internal used in Western Blot (WB). GTX80928

GTX80928 WB Image

WB analysis of HL-60(lane 1), K562(lane 2) cell lysate (35ug/lane) using GTX80928 NCX1 antibody, Internal.

REFERENCE

Application Reference

Lopez-Charcas O et al. Sci Rep 2018; 8 (1) : 12995 The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399