APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 2 μg/ml |
| 1 μg/ml |
| 1:10-1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein: NR2B subunit of amino acid residues 934-1457.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
glutamate ionotropic receptor NMDA type subunit 2B , EIEE27 , GluN2B , MRD6 , NMDAR2B , NR2B , NR3 , hNR3
Cellular Localization
Cell membrane
Background
This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
![Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691](/templates/default/js/lightbox/images/loading.gif "Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691")
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GTX80691 IHC-P Image
IHC-P analysis of human breast tissue using GTX80691 NMDAR2B antibody [NR2B].
Right : Primary antibody
Left : Negative control without primary antibody
Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min
Dilution : 1:20
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GTX80691 WB Image
WB analysis of mouse brain tissue using GTX80691 NMDAR2B antibody [NR2B].
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REFERENCE
There are currently no references for NMDAR2B antibody [NR2B] (GTX80691). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NMDAR2B antibody [NR2B] (GTX80691). Be the first to share your experience with this product.
![Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691](/upload/website/prouct_img/small/GTX80691/GTX80691_1408_IHC-P_w_23061322_716.webp "Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691")
![Anti-NMDAR2B antibody [NR2B] used in Western Blot (WB). GTX80691](/upload/website/prouct_img/small/GTX80691/GTX80691_1952_WB_w_23061322_128.webp "Anti-NMDAR2B antibody [NR2B] used in Western Blot (WB). GTX80691")
![Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691](/upload/website/prouct_img/normal/GTX80691/GTX80691_1408_IHC-P_w_23061322_716.webp "Anti-NMDAR2B antibody [NR2B] used in IHC (Paraffin sections) (IHC-P). GTX80691")
![Anti-NMDAR2B antibody [NR2B] used in Western Blot (WB). GTX80691](/upload/website/prouct_img/normal/GTX80691/GTX80691_1952_WB_w_23061322_128.webp "Anti-NMDAR2B antibody [NR2B] used in Western Blot (WB). GTX80691")