GeneTex

  • Country / Location Selection

United States (US)

NOD2 antibody, Internal

Anti-NOD2 antibody, Internal used in Western Blot (WB). GTX89233

Cat. No. GTX89233

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all NOD2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.3μg/ml
Not tested in other applications.

Calculated MW

115 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89233-PEP).

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence KFRFTDRERHCSPTD, from the internal region of the protein sequence according to NP_071445.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nucleotide binding oligomerization domain containing 2 , ACUG , BLAU , BLAUS , CARD15 , CD , CLR16.3 , IBD1 , NLRC2 , NOD2B , PSORAS1 , YAOS

Cellular Localization

Cytoplasm , Membrane , Mitochondrion

Background

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Database

Research Area

DATA IMAGES

Anti-NOD2 antibody, Internal used in Western Blot (WB). GTX89233

GTX89233 WB Image

WB analysis of human peripheral blood mononucleocyte lysate using GTX89233 NOD2 antibody, Internal.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for NOD2 antibody, Internal (GTX89233). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for NOD2 antibody, Internal (GTX89233). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399