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NR0B2 antibody

Anti-NR0B2 antibody used in Western Blot (WB). GTX54598
Anti-NR0B2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54598
Anti-NR0B2 antibody used in Western Blot (WB). GTX54598
Anti-NR0B2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54598

Cat. No. GTX54598

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all NR0B2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-257 of human NR0B2 (NP_068804.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor subfamily 0 group B member 2 , SHP , SHP1

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-NR0B2 antibody used in Western Blot (WB). GTX54598

GTX54598 WB Image

WB analysis of various sample lysates using GTX54598 NR0B2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NR0B2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54598

GTX54598 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX54598 NR0B2 antibody.
Blue : DAPI

Anti-NR0B2 antibody used in Western Blot (WB). GTX54598

GTX54598 WB Image

WB analysis of mouse liver tissue lysate using GTX54598 NR0B2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-NR0B2 antibody used in IHC (Paraffin sections) (IHC-P). GTX54598

GTX54598 IHC-P Image

IHC-P analysis of rat liver tissue using GTX54598 NR0B2 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399