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NUMB antibody [1A7]

Overexpression
Anti-NUMB antibody [1A7] used in Western Blot (WB). GTX83974
Anti-NUMB antibody [1A7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83974
Anti-NUMB antibody [1A7] used in Western Blot (WB). GTX83974
Anti-NUMB antibody [1A7] used in Flow cytometry (FACS). GTX83974

Cat. No. GTX83974

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1A7

Isotype

 IgG1

Application

 WB, ICC/IF, FACS

Reactivity

 Human, Dog
Package
100 μl ($519)
See all NUMB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000
ICC/IF 1:100
FACS 1:100
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.6 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527

Background

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Database

Research Area

DATA IMAGES

Anti-NUMB antibody [1A7] used in Western Blot (WB). GTX83974

GTX83974 WB Image

Overexpression

WB analysis of HEK293T cells transfected with NUMB plasmid (Right) or empty vector (Left) for 48 hrs using GTX83974 NUMB antibody [1A7].
Loading : 5 ug per lane

Anti-NUMB antibody [1A7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83974

GTX83974 ICC/IF Image

ICC/IF analysis of COS7 cells transiently transfected with NUMB plasmid using GTX83974 NUMB antibody [1A7].

Anti-NUMB antibody [1A7] used in Western Blot (WB). GTX83974

GTX83974 WB Image

WB analysis of various cell lines using GTX83974 NUMB antibody [1A7].
Loading : 10 ug per lane
Dilution : 1:200

Anti-NUMB antibody [1A7] used in Flow cytometry (FACS). GTX83974

GTX83974 FACS Image

FACS analysis of HEK293T cells transfected with either NUMB plasmid(Red) or empty vector control plasmid(Blue) using GTX83974 NUMB antibody [1A7].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519