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Nav1.1 antibody

Anti-Nav1.1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54841
Anti-Nav1.1 antibody used in Western Blot (WB). GTX54841
Anti-Nav1.1 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54841

Cat. No. GTX54841

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-Fr, IP

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all Nav1.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

229 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.6 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)TASEHSREPSAAGRLSD, corresponding to amino acid residues 465-481 (Intracellular loop between domains I and II) of rat NaV1.1 (Accession  : P04774).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sodium voltage-gated channel alpha subunit 1

Cellular Localization

Cell membrane

Background

has voltage gated sodium ion channel activity; plays a role in generation of action potential [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Nav1.1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54841

GTX54841 ICC/IF Image

ICC/IF analysis of PFA-fixed rat DRG cells using GTX54841 Nav1.1 antibody.
Panel A : Primary antibody
Panel B : DNA dye Hoechst 33342
Panel C : Merged images of panels A and B
Dilution : 1:200

Anti-Nav1.1 antibody used in Western Blot (WB). GTX54841

GTX54841 WB Image

WB analysis of rat brain membrane lysate using GTX54841 Nav1.1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-Nav1.1 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54841

GTX54841 IHC-Fr Image

IHC-Fr analysis of mouse cerebellum tissue using GTX54841 Nav1.1 antibody.
Panel A : The distribution of NaV1.1 (red) forms a band (arrows) in the molecular layer (Mol), close to the Purkinje cell bodies.
Panel B : Purkinje nerve cells are stained with mouse anti-Parvalbumin (green).
Panel C : Confocal merge of NaV1.1 and Parvalbumin.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639