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Nucleophosmin antibody [NA24]

Anti-Nucleophosmin antibody [NA24] used in IHC (Paraffin sections) (IHC-P). GTX17759

Cat. No. GTX17759

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NA24

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Nucleophosmin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 amino acid of ALK protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

B23 , NPM , NPM1 , nucleophosmin , Nucleophosmin , nucleophosmin 1

Cellular Localization

Nucleus,Nucleolus,Nucleoplasm,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome

Background

The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Nucleophosmin antibody [NA24] used in IHC (Paraffin sections) (IHC-P). GTX17759

GTX17759 IHC-P Image

IHC-P analysis of human skin tissue using GTX17759 Nucleophosmin antibody [NA24].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529