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P2X7 antibody

Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284
Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284
Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284

Cat. No. GTX111284

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all P2X7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

Predict Reactivity

Bovine, Dog, Guinea pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.82 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the Extracellular domain of human P2X7. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11171397

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2X 7 , P2X7

Cellular Localization

Cell membrane

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284

GTX111284 IHC-P Image

P2X7 antibody detects P2X7 protein at cell membrane and cytoplasm in mouse brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse brain.
P2X7 antibody (GTX111284) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284

GTX111284 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human breast cancer, using P2X7(GTX111284) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-P2X7 antibody used in IHC (Paraffin sections) (IHC-P). GTX111284

GTX111284 IHC-P Image

P2X7 antibody detects P2X7 protein at cell membrane and cytoplasm in rat lymph node by immunohistochemical analysis.
Sample: Paraffin-embedded rat lymph node.
P2X7 antibody (GTX111284) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399
$ 169