APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
17 - 34 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Dog, Bat, Elephant, Gibbon, Gorilla, Marmoset, Orangutan, Panda, Pufferfish(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human P2RY6 / P2Y6.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
pyrimidinergic receptor P2Y6 , P2RY6 , P2Y6
Cellular Localization
Cell membrane
Background
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
Database
Research Area
DATA IMAGES
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GTX13106 IHC-P Image
IHC-P analysis of brain, glioblastoma tissue using GTX13106 P2Y6 antibody.
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GTX13106 IHC-P Image
IHC-P analysis of human breast, carcinoma tissue using GTX13106 P2Y6 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX13106 IHC-P Image
IHC-P analysis of breast, adenocarcinoma tissue using GTX13106 P2Y6 antibody.
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GTX13106 IHC-P Image
IHC-P analysis of human spleen, red pulp tissue using GTX13106 P2Y6 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX13106 IHC-P Image
IHC-P analysis of human lymph node, non-hodgkins lymphoma tissue using GTX13106 P2Y6 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX13106 IHC-P Image
IHC-P analysis of human pancreas, carcinoma tissue using GTX13106 P2Y6 antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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