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PAK6 antibody

Anti-PAK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX78127
Anti-PAK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX78127

Cat. No. GTX78127

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Dog, Monkey, Horse
Package
25 μg ($299)
See all PAK6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 3.5 μg/ml
Not tested in other applications.

Calculated MW

75 kDa. ( Note )

Predict Reactivity

Mouse, Rabbit, Goat, Bovine, Hamster, Bat, Elephant, Gibbon, Gorilla, Marmoset, Orangutan, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from Linker domain of human PAK6.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_425075

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

p21 (RAC1) activated kinase 6 , PAK5 , PAK6

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Database

Research Area

DATA IMAGES

Anti-PAK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX78127

GTX78127 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX78127 PAK6 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-PAK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX78127

GTX78127 IHC-P Image

IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX78127 PAK6 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

Application Reference

Zapatero A et al. Urol Oncol 2014; Predictive value of PAK6 and PSMB4 expression in patients with localized prostate cancer treated with dose-escalation radiation therapy and androgen deprivation therapy.
Application : IHC-P
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299