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PAN-SHANK antibody [S23b-49]

Anti-PAN-SHANK antibody [S23b-49] used in Western Blot (WB). GTX42006

Cat. No. GTX42006

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 S23b-49

Isotype

 IgG1

Application

 WB, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SHANK products

APPLICATION

Application Note

We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).

Calculated MW

160 kDa. ( Note )

Product Note

Recognzies Shank1, 2 and 3.

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Fusion protein amino acids 84-309 of rat Shank2; accession number Q9QX74

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cytoplasm, postsynaptic density of neuronal cells. Colocalizes with cortactin in growth cones in differentiating hippocampal neurons.

Background

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Research Area

DATA IMAGES

Anti-PAN-SHANK antibody [S23b-49] used in Western Blot (WB). GTX42006

GTX42006 WB Image

Western blot analysis of pan-shank in rat brain membrane lysates using a 1:1000 dilution of GTX42006.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 399