PDE1B antibody [5C4A3]

Cat. No. GTX60718

Host	Mouse
Clonality	Monoclonal
Clone Name	5C4A3
Isotype	IgG1
Application	WB, IHC-P, FACS, ELISA
Reactivity	Human, Rat
Package	100 μg ($409)

See all PDE1B products

Datasheet
Document

View product citations for antibody GTX60718 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1/500 - 1/2000
IHC-P	1/200 - 1/1000
FACS	1/200 - 1/400
ELISA	1/10000

Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 1B , HEL-S-79p , PDE1B1 , PDES1B

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Database

Gene ID: 5153 PDE1B
UniProt: Q01064 PDE1B

Research Area

DATA IMAGES

GTX60718 FACS Image

FACS analysis of A549 cells using GTX60718 PDE1B antibody [5C4A3].
Green : PDE1B
Red : negative control

GTX60718 WB Image

WB analysis of HEK293 (1) and PDE1B (AA: 370-536)-hIgGFc transfected HEK293 (2) cell lysate using GTX60718 PDE1B antibody [5C4A3].

GTX60718 WB Image

WB analysis of PC-12 cell lysate using GTX60718 PDE1B antibody [5C4A3].

GTX60718 IHC-P Image

IHC-P analysis of ovarian cancer tissue using GTX60718 PDE1B antibody [5C4A3].

GTX60718 ELISA Image

ELISA analysis of antigen using GTX60718 PDE1B antibody [5C4A3].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

GTX60718 IHC-P Image

IHC-P analysis of rectum cancer tissue using GTX60718 PDE1B antibody [5C4A3].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 409

Qty

PDE1B antibody [5C4A3]

Cat. No. GTX60718

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Calculated MW

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

Note

TARGET

Synonyms

Cellular Localization

Background

Database

Research Area

DATA IMAGES

GTX60718 FACS Image

GTX60718 WB Image

GTX60718 WB Image

GTX60718 IHC-P Image

GTX60718 ELISA Image

GTX60718 IHC-P Image

REFERENCE

REVIEW

Product

Research

Support

Company

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