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PDE1B antibody

Anti-PDE1B antibody used in IHC (Paraffin sections) (IHC-P). GTX54568
Anti-PDE1B antibody used in Western Blot (WB). GTX54568
Anti-PDE1B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54568

Cat. No. GTX54568

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all PDE1B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 1B , HEL-S-79p , PDE1B1 , PDES1B

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-PDE1B antibody used in IHC (Paraffin sections) (IHC-P). GTX54568

GTX54568 IHC-P Image

IHC-P analysis of rat brain tissue using GTX54568 PDE1B antibody.
Dilution : 1:100

Anti-PDE1B antibody used in Western Blot (WB). GTX54568

GTX54568 WB Image

WB analysis of various sample lysates using GTX54568 PDE1B antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-PDE1B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54568

GTX54568 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX54568 PDE1B antibody.
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399