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PDE6B antibody

Anti-PDE6B antibody used in Western Blot (WB). GTX33395
Anti-PDE6B antibody used in IHC (Paraffin sections) (IHC-P). GTX33395
Anti-PDE6B antibody used in IHC (Paraffin sections) (IHC-P). GTX33395

Cat. No. GTX33395

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Mouse, Rat
Package
100 μl ($399)
See all PDE6B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

98 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 6B , CSNB3 , CSNBAD2 , GMP-PDEbeta , PDEB , RP40 , rd1

Background

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES

Anti-PDE6B antibody used in Western Blot (WB). GTX33395

GTX33395 WB Image

WB analysis of various sample lysates using GTX33395 PDE6B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PDE6B antibody used in IHC (Paraffin sections) (IHC-P). GTX33395

GTX33395 IHC-P Image

IHC-P analysis of mouse retina tissue using GTX33395 PDE6B antibody.
Dilution : 1:200

Anti-PDE6B antibody used in IHC (Paraffin sections) (IHC-P). GTX33395

GTX33395 IHC-P Image

IHC-P analysis of rat retina tissue using GTX33395 PDE6B antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399