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PDGF Receptor beta antibody [18A2]

Overexpression
Anti-PDGF Receptor beta antibody [18A2] used in Flow cytometry (FACS). GTX80295

Cat. No. GTX80295

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 18A2

Isotype

 IgG1

Application

 ICC/IF, FACS

Reactivity

 Human
Package
100 μg ($399)
See all PDGF Receptor beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

124 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CD140b-transfected NIH 3T3 cells

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR1 , PDGFRB , PENTT , platelet derived growth factor receptor beta , PDGF Receptor beta , CD140b , PDGFR beta

Cellular Localization

Cell membrane,Cytoplasmic vesicle,Lysosome lumen

Background

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-PDGF Receptor beta antibody [18A2] used in Flow cytometry (FACS). GTX80295

GTX80295 FACS Image

Overexpression

FACS analysis of human CD140b / PDGF-RB stable transfectants using GTX80295 PDGF Receptor beta antibody [18A2].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399