APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:400 - 1:1000 |
| 1:50 - 1:500 |
| 15μl / 10⁶ cells |
Not tested in other applications.
Calculated MW
Product Note
This antibody is specific for PDGF receptor beta and does not cross-react with alpha.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant hPGFDR beta N-terminal
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR1 , PDGFRB , PENTT , platelet derived growth factor receptor beta , PDGF Receptor beta , CD140b , PDGFR beta
Cellular Localization
Cell membrane,Cytoplasmic vesicle,Lysosome lumen
Background
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
![Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458](/templates/default/js/lightbox/images/loading.gif "Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458")
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GTX52458 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52458 PDGF Receptor beta antibody [5C37].
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REFERENCE
There are currently no references for PDGF Receptor beta antibody [5C37] (GTX52458). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PDGF Receptor beta antibody [5C37] (GTX52458). Be the first to share your experience with this product.
![Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458](/upload/website/prouct_img/small/GTX52458/GTX52458_20191119_IHC-P_w_23060900_210.webp "Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458")
![Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458](/upload/website/prouct_img/normal/GTX52458/GTX52458_20191119_IHC-P_w_23060900_210.webp "Anti-PDGF Receptor beta antibody [5C37] used in IHC (Paraffin sections) (IHC-P). GTX52458")