APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:1000 |
| 1:50 - 1:100 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human PDGFR beta around the phosphorylation site of tyrosine 751 (V-D-Yp-V-P).
Purification
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum
Conjugation
Unconjugated
RRID
AB_11163068
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR1,PDGFRB,PENTT,platelet derived growth factor receptor beta,PDGF Receptor beta,CD140b,PDGFR beta
Cellular Localization
Cell membrane,Cytoplasmic vesicle,Lysosome lumen
Background
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
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GTX78970 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX78970 PDGF Receptor beta (phospho Tyr751) antibody.
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GTX78970 WB Image
WB analysis of NIH/3T3 cells treated with PDGF lysate using GTX78970 PDGF Receptor beta (phospho Tyr751) antibody.
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REFERENCE
There are currently no references for PDGF Receptor beta (phospho Tyr751) antibody (GTX78970). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PDGF Receptor beta (phospho Tyr751) antibody (GTX78970). Be the first to share your experience with this product.
