APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to product this antibody is available for purchase (Catalog Number:GTX26037-PEP).
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence PITQDNAVLHLPLC, from the N Terminus of the protein sequence according to NP_835260.2.
Purification
Purified by ammonium sulphate precipitation followed by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
AIPC,PAPIN,PDZ domain containing 2,PDZD2,PDZK3,PIN1
Cellular Localization
Nucleus,Cytoplasm,Endoplasmic reticulum,Secreted
Background
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.
Database
Research Area
DATA IMAGES
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GTX26037 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX26037 PDZK3 antibody, N-term.
Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6
Dilution : 6μg/ml
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GTX26037 ICC/IF Image
ICC/IF analysis of paraformaldehyde fixed U2OS cells using GTX26037 PDZK3 antibody, N-term.
Green : Primary antibody
Blue : DAPI
Negative control: Unimmunized goat IgG
Dilution : 10μg/ml
Green : Primary antibody
Blue : DAPI
Negative control: Unimmunized goat IgG
Dilution : 10μg/ml
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REFERENCE
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REVIEW
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