APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human PGC-1alpha expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
PPARG coactivator 1 alpha , LEM6 , PGC-1(alpha) , PGC-1alpha , PGC-1v , PGC1 , PGC1A , PPARGC1
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX60496 WB Image
WB analysis of human PGC1 alpha (AA: 570-798) recombinant protein using GTX60496 PGC1 alpha antibody [1G8].
|
|
GTX60496 WB Image
WB analysis of HEK293 (1) and PGC1 alpha-hIgGFc transfected HEK293 (2) cell lysate using GTX60496 PGC1 alpha antibody [1G8].
|
|
GTX60496 ELISA Image
ELISA analysis of antigen using GTX60496 PGC1 alpha antibody [1G8].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng
|
REFERENCE
There are currently no references for PGC1 alpha antibody [1G8] (GTX60496). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PGC1 alpha antibody [1G8] (GTX60496). Be the first to share your experience with this product.