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PHLPP1 antibody

Anti-PHLPP1 antibody used in Western Blot (WB). GTX64568
Anti-PHLPP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64568
Anti-PHLPP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64568

Cat. No. GTX64568

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PHLPP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

185 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

PH domain and leucine rich repeat protein phosphatase 1 , PHLPP , PLEKHE1 , PPM3A , SCOP

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]

Database

Research Area

DATA IMAGES

Anti-PHLPP1 antibody used in Western Blot (WB). GTX64568

GTX64568 WB Image

WB analysis of various sample lysates using GTX64568 PHLPP1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PHLPP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64568

GTX64568 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64568 PHLPP1 antibody.
Dilution : 1:100

Anti-PHLPP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64568

GTX64568 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX64568 PHLPP1 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399