GeneTex

  • Country / Location Selection

United States (US)

PODXL antibody [PODXL/2185]

Anti-PODXL antibody [PODXL/2185] used in IHC (Paraffin sections) (IHC-P). GTX18082
Anti-PODXL antibody [PODXL/2185] used in Protein Array (Protein Array). GTX18082
Anti-PODXL antibody [PODXL/2185] used in IHC (Paraffin sections) (IHC-P). GTX18082

Cat. No. GTX18082

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PODXL/2185

Isotype

 IgG1

Application

 IHC-P, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all PODXL products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 min at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Gp200 , PC , PCLP , PCLP1 , PODXL , podocalyxin like , Podocalyxin , GCTM-2 antigen , GCTM2

Cellular Localization

Apical cell membrane,Cell projection,Lamellipodium,Filopodium,Ruffle,Microvillus,Membrane raft,Membrane

Background

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PODXL antibody [PODXL/2185] used in IHC (Paraffin sections) (IHC-P). GTX18082

GTX18082 IHC-P Image

IHC-P analysis of human endometrium tissue using GTX18082 PODXL antibody [PODXL/2185].

Anti-PODXL antibody [PODXL/2185] used in Protein Array (Protein Array). GTX18082

GTX18082 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using Podocalyxin Mouse Monoclonal Antibody (PODXL/2185). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-PODXL antibody [PODXL/2185] used in IHC (Paraffin sections) (IHC-P). GTX18082

GTX18082 IHC-P Image

IHC-P analysis of human placenta tissue using GTX18082 PODXL antibody [PODXL/2185].

REFERENCE

There are currently no references for PODXL antibody [PODXL/2185] (GTX18082). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PODXL antibody [PODXL/2185] (GTX18082). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529